Painful at times, heartbreaking at others, Pieces of You and Me is the story of Jesse and Rupert, torn apart and reunited with many years, relationships and pain between them. They were friends since birth, lovers since sixteen. They fall apart when his demanding father sends him from the UK to Harvard. Each of them suffers later from debilitating diseases that neither wants to bring up or discuss. When they meet again, the lack of openness and honesty threatens to tear them apart again but the strong desire to be a loving unit at last stands frim as they slowly, painfully navigate the chance for a future.